过敏毒素C5a/补体C5a抗体

?过敏毒素C5a/补体C5a抗体Quantity size:

0.2ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a,过敏毒素C5a/补体C5a抗体 which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement 过敏毒素C5a/补体C5a抗体component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis. [provided by RefSeq, Jul 2008].

Also known as:

过敏毒素C5a/补体C5a抗体Complement C5; Complement C5a; Hemolytic complement; C5a anaphylatoxin; C5a; IFN-gamma-complement component C5a fusion protein; Complement-C5; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4;

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Mouse, .

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Immunogen: KLH conjugated synthetic peptide derived from mouse C5a (725-770aa).

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过敏毒素C5a/补体C5a抗体Predicted Molecular Weight: 9/113kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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