供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL1594R |
CAS号: |
?α-连环蛋白抗体Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The distinct peripheral cytosolic proteins, alpha, beta and gamma-catenin (102, 94 and 86 kDa) found in many tissues bind to the conserved cytoplasmic tail domain of the cell-adhesion cadherins.α-连环蛋白抗体 Catenins link E-cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt-1 proto-oncogene. They are good candidates for mediating transduction of cell-cell contact positional signals to the cell interior. Absence of alpha-catenin is found in certain tumor cell lines and reduced levels in certain human carcinomas. Beta-catenin binds directly to the cytoplasmic tail of E-cadherin.α-连环蛋白抗体 It binds to the N-terminus of alpha-catenin and interacts with the protein product of the tumor suppressor gene APC. This interaction involves a 15-aa repeat in the APC. Beta-catenin cell levels seem to be controlled by APC. The central core region of beta-catenin is involved in mediation of cadherin-catenin complex interaction with EGFR.
α-连环蛋白抗体Also known as:
alpha 1 Catenin; Alpha-Catenin; alpha catenin; alpha E catenin; alphaE catenin; Cadherin associated protein 102kDa; Cadherin associated protein; CAP 102; CAP102; Catenin (cadherin associated protein) alpha 1 102kDa; Catenin alpha 1; CTNNA 1; CTNNA1; Alpha-cats; FLJ36832; NY REN 13 antigen; CTNA1_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, .
●
Immunogen: KLH conjugated synthetic peptide derived from human Catenin.
●
α-连环蛋白抗体Predicted Molecular Weight: 102kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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kl061Ra01白介素15(IL15)多克隆抗体Polyclonal Antibody to Interleukin 15 (IL15)
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kl062Ga01白介素16(IL16)多克隆抗体Polyclonal Antibody to Interleukin 16 (IL16)
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kl062Mu01白介素16(IL16)多克隆抗体Polyclonal Antibody to Interleukin 16 (IL16)
kl062Po01白介素16(IL16)多克隆抗体Polyclonal Antibody to Interleukin 16 (IL16)
kl062Ra01白介素16(IL16)多克隆抗体Polyclonal Antibody to Interleukin 16 (IL16)
kl063Bo01白介素17(IL17)多克隆抗体Polyclonal Antibody to Interleukin 17 (IL17)
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kl063Ga01白介素17(IL17)多克隆抗体Polyclonal Antibody to Interleukin 17 (IL17)
kl063Hu01白介素17(IL17)多克隆抗体Polyclonal Antibody to Interleukin 17 (IL17)
kl063Mu01白介素17(IL17)多克隆抗体Polyclonal Antibody to Interleukin 17 (IL17)
kl063Po01白介素17(IL17)多克隆抗体Polyclonal Antibody to Interleukin 17 (IL17)
kl063Ra01白介素17(IL17)多克隆抗体Polyclonal Antibody to Interleukin 17 (IL17)
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