磷酸化着丝粒蛋白A

磷酸化着丝粒蛋白AQuantity size:

0.1ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes磷酸化着丝粒蛋白Aa centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the 磷酸化着丝粒蛋白A(H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq].

Also known as:

CENPA (phospho S7); p-CENPA (phospho S7); CENP A; CENP-A; Centromere autoantigen A; Centromere protein A 17kDa; centromere protein A; centromeric protein A; Histone H3 like centromeric protein A; cenpa; CENPA_HUMAN;磷酸化着丝粒蛋白A Histone H3-like centromeric protein A.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Rabbit, .

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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human CENP-A around the phosphorylation site of Ser7 [RR(p-S)RK].

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磷酸化着丝粒蛋白APredicted Molecular Weight: 15kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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