磷酸化Crk p38抗体

磷酸化Crk p38抗体Quantity size:

0.1ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Crk p38 (CrkII) is an isoform of the protein Crk. CrkI and CrkII are produced from the same crk gene by alternative splicing. The two isoforms differ in their biological activities with CrkII having less transforming activity than CrkI. Crk p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins.磷酸化Crk p38抗体 It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Crk is believed to be a regulator of invasive responses because increased levels of the protein have been 磷酸化Crk p38抗体observed in multiple human cancers. In vivo studies have demonstrated that decreased levels of Crk remarkably inhibits tumor formation and its invasive growth.

Also known as:

Crk p38 (phospho Y221); p-Crk p38 (phospho Y221); p-CRK(phospho-Tyr221); p-CRK(phospho-Y221); Crk p38; CRK CRK isoform 2; CRK isoform II; CRKII; p38; Proto oncogene C crk;磷酸化Crk p38抗体 v crk avian sarcoma virus CT10 oncogene homolog ; v crk sarcoma virus CT10 oncogene homolog; v crk sarcoma virus CT10 oncogene homolog (avian); Adapter molecule crk; Avian sarcoma virus CT10 (v crk) oncogene homolog; CRK_HUMAN

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit, .

●

磷酸化Crk p38抗体Immunogen: KLH conjugated Synthesised phosphopeptide derived from human Crk p38 around the phosphorylation site of Tyr221 [GP(p-Y)AQ].

●

Predicted Molecular Weight: 38kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl095Mu01巨噬细胞炎性蛋白3α(MIP3α)多克隆抗体Polyclonal Antibody to Macrophage Inflammatory Protein 3 Alpha (MIP3a)

kl095Po01巨噬细胞炎性蛋白3α(MIP3α)多克隆抗体Polyclonal Antibody to Macrophage Inflammatory Protein 3 Alpha (MIP3a)

kl095Ra01巨噬细胞炎性蛋白3α(MIP3α)多克隆抗体Polyclonal Antibody to Macrophage Inflammatory Protein 3 Alpha (MIP3a)

kl096Bo01巨噬细胞炎性蛋白3β(MIP3β)多克隆抗体Polyclonal Antibody to Macrophage Inflammatory Protein 3 Beta (MIP3b)

kl096Ca01巨噬细胞炎性蛋白3β(MIP3β)多克隆抗体Polyclonal Antibody to Macrophage Inflammatory Protein 3 Beta (MIP3b)

kl096Hu01巨噬细胞炎性蛋白3β(MIP3β)多克隆抗体Polyclonal Antibody to Macrophage Inflammatory Protein 3 Beta (MIP3b)

kl096Mu01巨噬细胞炎性蛋白3β(MIP3β)多克隆抗体Polyclonal Antibody to Macrophage Inflammatory Protein 3 Beta (MIP3b)

kl096Po01巨噬细胞炎性蛋白3β(MIP3β)多克隆抗体Polyclonal Antibody to Macrophage Inflammatory Protein 3 Beta (MIP3b)

kl096Ra01巨噬细胞炎性蛋白3β(MIP3β)多克隆抗体Polyclonal Antibody to Macrophage Inflammatory Protein 3 Beta (MIP3b)

kl097Bo01基质金属蛋白酶1(MMP1)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 1 (MMP1)

kl097Eq01基质金属蛋白酶1(MMP1)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 1 (MMP1)

kl097Hu01基质金属蛋白酶1(MMP1)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 1 (MMP1)

kl097Mu01基质金属蛋白酶1(MMP1)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 1 (MMP1)

kl097Ov01基质金属蛋白酶1(MMP1)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 1 (MMP1)

kl097Po01基质金属蛋白酶1(MMP1)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 1 (MMP1)

kl097Ra01基质金属蛋白酶1(MMP1)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 1 (MMP1)

kl097Rb51基质金属蛋白酶1(MMP1)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 1 (MMP1)

kl098Hu01基质金属蛋白酶10(MMP10)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10)

kl098Mu01基质金属蛋白酶10(MMP10)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10)

kl098Po01基质金属蛋白酶10(MMP10)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10)

kl098Ra01基质金属蛋白酶10(MMP10)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10)

kl099Bo01基质金属蛋白酶13(MMP13)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 13 (MMP13)

kl099Ca01基质金属蛋白酶13(MMP13)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 13 (MMP13)

kl099Cp01基质金属蛋白酶13(MMP13)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 13 (MMP13)