内皮因子维生素B12受体抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 内皮因子维生素B12受体抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Cubilin is an endocytic receptor that lacks a classical transmembrane region. It is a multidomain receptor that contains an amino terminal 110 residue segment followed by 8 epidermal growth factor (EGF)-like repeats and a contiguous stretch of 27 CUB domains. Cubilin acts as a receptor for内皮因子维生素B12受体抗体 intrinsic factor-vitamin B12 complexes. Cubilin is located within the epithelium of intestine and kidney. Cubilin co-localizes with and binds to Megalin, a 600kDa member of the LDL receptor family that is required for the internalization of cubilin-bound ligands, such as vitamin B12, apolipoprotein A1 and Albumin. Megalin specifically binds to cubilin in the amino terminal region that contains the EGF-like repeats and CUB domains 1 and 2. Mutations in Cubilin may play 内皮因子维生素B12受体抗体a role in autosomal recessive megaloblastic anemia also known as Imerslund-Grasbeck’s disease, which causes intestinal malabsorption of vitamin B12.

Also known as:

460 kDa receptor; cubilin (intrinsic factor-cobalamin receptor); Cubilin precursor; CUBN; IFCR; Intestinal intrinsic factor receptor; intrinsic factor B12-receptor; intrinsic factor-cobalamin receptor; 内皮因子维生素B12受体抗体intrinsic factor-vitamin B12 receptor; megaloblastic anemia 1; MGA1.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, .

●

Immunogen: KLH conjugated synthetic peptide derived from human Cubilin (48-90aa).

●

内皮因子维生素B12受体抗体Predicted Molecular Weight: 395kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl017Hu01上皮性钙黏附蛋白(CDHE)多克隆抗体Polyclonal Antibody to Cadherin, Epithelial (CDHE)

kl017Mu01上皮性钙黏附蛋白(CDHE)多克隆抗体Polyclonal Antibody to Cadherin, Epithelial (CDHE)

kl017Po01上皮性钙黏附蛋白(CDHE)多克隆抗体Polyclonal Antibody to Cadherin, Epithelial (CDHE)

kl017Ra01上皮性钙黏附蛋白(CDHE)多克隆抗体Polyclonal Antibody to Cadherin, Epithelial (CDHE)

kl019Hu01白介素8受体α(IL8Rα)多克隆抗体Polyclonal Antibody to Interleukin 8 Receptor Alpha (IL8Ra)

kl019Mu01白介素8受体α(IL8Rα)多克隆抗体Polyclonal Antibody to Interleukin 8 Receptor Alpha (IL8Ra)

kl019Ra01白介素8受体α(IL8Rα)多克隆抗体Polyclonal Antibody to Interleukin 8 Receptor Alpha (IL8Ra)

kl019Rb51白介素8受体α(IL8Rα)多克隆抗体Polyclonal Antibody to Interleukin 8 Receptor Alpha (IL8Ra)

kl021Ga01睫状神经营养因子(CNTF)多克隆抗体Polyclonal Antibody to Ciliary Neurotrophic Factor (CNTF)

kl021Hu01睫状神经营养因子(CNTF)多克隆抗体Polyclonal Antibody to Ciliary Neurotrophic Factor (CNTF)

kl021Mu01睫状神经营养因子(CNTF)多克隆抗体Polyclonal Antibody to Ciliary Neurotrophic Factor (CNTF)

kl021Po01睫状神经营养因子(CNTF)多克隆抗体Polyclonal Antibody to Ciliary Neurotrophic Factor (CNTF)

kl021Ra01睫状神经营养因子(CNTF)多克隆抗体Polyclonal Antibody to Ciliary Neurotrophic Factor (CNTF)

kl021Rb51睫状神经营养因子(CNTF)多克隆抗体Polyclonal Antibody to Ciliary Neurotrophic Factor (CNTF)

kl022Bo01血管内皮细胞蛋白C受体(PROCR)多克隆抗体Polyclonal Antibody to Protein C Receptor, Endothelial (PROCR)