电压依赖性钙通道Cav2.1抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 电压依赖性钙通道Cav2.1抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Cav2.1 is a voltage-sensitive calcium channels (VSCC) which belongs to the calcium channel alpha-1 subunit family. Cav2.1 mediates the entry of calcium ions into excitable cells and is also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. 电压依赖性钙通道Cav2.1抗体Cav2.1 (isoform alpha-1A) gives rise to P and/or Q-type calcium currents. Voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the pore-forming and voltage-sensitive alpha-1 subunit. 电压依赖性钙通道Cav2.1抗体In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity.

Also known as:

APCA; BI; Brain calcium channel 1; Brain calcium channel I; Cach4; Cacn3; Cacna1a; Cacnl1a4; Calcium channel alpha 1A subunit; Calcium channel L type alpha 1 polypeptide; Calcium channel L type alpha-1 polypeptide isoform 4; Calcium channel voltage dependent, P/Q type alpha 1A subunit;电压依赖性钙通道Cav2.1抗体 CAV2.1; EA2; FHM; HPCA; MHP; MHP1; RAT brain class A; RBA-I; SCA6; Voltage-dependent P/Q-type calcium channel alpha-1A subunit; Voltage-gated calcium channel alpha subunit Cav2.1; CAC1A_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Pig, Cow, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human CACNA1A.

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电压依赖性钙通道Cav2.1抗体Predicted Molecular Weight: 282kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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