供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL5046R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 胆固醇24S-羟化酶 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol,胆固醇24S-羟化酶 steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.
胆固醇24S-羟化酶Cyp46 is also known as 24S-cholesterol hydroxylase.
Also known as:
Cholesterol 24-hydroxylase; CP46; CYP46; CP46A_HUMAN; cytochrome P450 family 46.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, 胆固醇24S-羟化酶Rat, Dog, Cow, Horse, Rabbit, Sheep, .
●
Immunogen: KLH conjugated synthetic peptide derived from human CYP46.
●
Predicted Molecular Weight: 57kDa.
Storage:
胆固醇24S-羟化酶Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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