磷酸化细胞分裂周期蛋白25抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化细胞分裂周期蛋白25抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups.磷酸化细胞分裂周期蛋白25抗体 CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

磷酸化细胞分裂周期蛋白25抗体Also known as:

cdc25A (Phospho-Ser124); cdc25A (Phospho Ser124); cdc25A (Phospho S124); Cdc 25a; CDC25A2; Cell division cycle 25 homolog A (S. pombe); Cell division cycle 25A; Cell division cycle 25A isoform a; Cell division cycle 25A isoform b; D9Ertd393e; Dual specificity phosphatase CDC25A; EC 3.1.3.48;磷酸化细胞分裂周期蛋白25抗体 M phase inducer phosphatase 1; MGC115549; CDC25A; CDC25A2 CAG isoform; M-phase inducer phosphatase 1; MPIP1_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, .

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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human cdc25A around the phosphorylation site of Ser124 [SH(p-S)DS].

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磷酸化细胞分裂周期蛋白25抗体Predicted Molecular Weight: 59kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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