磷酸化细胞周期检测点激酶1抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化细胞周期检测点激酶1抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I.磷酸化细胞周期检测点激酶1抗体 Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2011].

磷酸化细胞周期检测点激酶1抗体Also known as:

Chk1 (Phospho-Ser317); CHEK1 (phospho Ser317); CHEK1 (phospho Ser317); p-CHEK1 (Ser317); Cell cycle checkpoint kinase; Checkpoint, S. pombe, homolog of, 1; Checkpoint kinase 1; Checkpoint kinase 1 homolog (S. pombe); CHEK 1; CHEK-1; CHEK1; Chk 1; Chk1; CHK1 checkpoint homolog (S. pombe); EC 2.7.11.1; rad27; Serine/threonine protein kinase Chk1; Serine/threonine-protein kinase CHK1; STT3, subunit of the oligosaccharyltransferase complex,磷酸化细胞周期检测点激酶1抗体 homolog A (S. cerevisiae); C85740; CHK1_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Pig, Horse, Rabbit, .

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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human CHEK1 around the phosphorylation site of Ser317.

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磷酸化细胞周期检测点激酶1抗体Predicted Molecular Weight: 54kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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