| 供货周期： | 现货 |
| 品牌： | 康朗生物 |
| 规格： | 0.1ml/0.2ml |
| 货号： | KL5281R |
| CAS号： |
Quantity size:
0.2ml
Concentration:
1mg/ml周期素E2抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The human Cyclin E2 gene encodes a 404 amino acid protein that is most closely related to Cyclin E. Cyclin E2 mRNA levels peaks at the G1 / S transition. Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27 (Kip1) and p21 (Cip1). 周期素E2抗体Cyclin E2 / Cdk2 phosphorylates histone H1 in vitro. G1 cyclin E controls the initiation of DNA synthesis by activating CDK2. Abnormally high levels of cyclin E expression have frequently been observed in human cancers. Unlike Cyclin E1, which is expressed in great majority of proliferating normal and neoplastically transformed cells,周期素E2抗体 Cyclin E2 levels are low to undetectable in non transformed cells and increase significantly in neoplasm derived cells.
Also known as:
CCN E2; CCNE 2; CCNE2; CCNE2 protein; CYC E2; CYCE 2; CYCE2; CyclinE2; G1/S-specific cyclin E2; G1/S-specific cyclin E2; CCNE2_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity 周期素E2抗体purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, .
●
Immunogen: KLH conjugated synthetic peptide derived from human Cyclin E2.
●
Predicted Molecular Weight: 44kDa.
周期素E2抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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