结肠和肝肿瘤高表达蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml  结肠和肝肿瘤高表达蛋白抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

CKAP5 is a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation;结肠和肝肿瘤高表达蛋白抗体 it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified.

结肠和肝肿瘤高表达蛋白抗体Also known as:

Ch TOG protein; chTOG; CHTOG protein; CKAP5_HUMAN; CKAP 5; CKAP5; CKAP5 protein; Colonic and hepatic tumor over expressed; Colonic and hepatic tumor over expressed protein; Colonic and hepatic tumor overexpressed protein; Cytoskeleton associated protein 5; FLJ35359; KIAA0097; TOG; TOGp.

Specificity:

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Rabbit Polyclonal IgG, 结肠和肝肿瘤高表达蛋白抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Horse, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human CKAP5/ch TOG.

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结肠和肝肿瘤高表达蛋白抗体Predicted Molecular Weight: 225kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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