细胞粘附分子3抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 细胞粘附分子3抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Immunoglobulin superfamily member 4B (Cell adhesion molecule 3, Nectin-like protein 1) is a nectin family gene product that contains 2 Ig-like C2-type (immunoglobulin-like) domains and an Ig-like V-type (immunoglobulin-like) domain. 细胞粘附分子3抗体IGSF4B is a single-pass type I membrane protein that localizes to cell-cell interacting sites along the plasma membrane. IGSF4B functions as a cell adhesion molecule at cell-cell junctions. IGSF4B can be found as a homodimer and has a dual calcium-independent adhesion function; a homophilic cell-cell interaction and a heterophilic cell-cell interaction involving 细胞粘附分子3抗体IGSF4, Nectin 1 and Nectin 3. IGSF4B may also interact with EPB41L1 which has a potential for regulating structure or function of cell-cell junctions By similarity. Isoform 1 is expressed in adult and fetal brain. Isoform 2 is highly expressed in the cerebellum but is also weakly expressed in placenta. IGSF4B has been found to be markedly over-expressed in glioma cell lines and prostate cancer cell lines.

Also known as:

Brain immunoglobulin receptor;细胞粘附分子3抗体Synaptic cell adhesion molecule 3; Necl 1; synCAM3; CADM 3; Cell adhesion molecule 3; FLJ10698; IGSF4B; Immunoglobulin superfamily member 4B; NECL1; Nectin like protein 1; TSLC1 like protein 1; TSLL1; CADM3_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human CADM3.

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细胞粘附分子3抗体Predicted Molecular Weight: 41kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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