信号转导蛋白亚基4抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 信号转导蛋白亚基4抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, 信号转导蛋白亚基4抗体leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

信号转导蛋白亚基4抗体Also known as:

CH4; COP9 (constitutive photomorphogenic) homolog subunit 4; COP9 complex homolog subunit 4; COP9 complex S4; COP9 constitutive photomorphogenic homolog subunit 4; COP9 signalosome complex subunit 4; COP9 signalosome subunit 4; COPS4; CSN complex subunit 4; CSN4; CSN4 SCHPO; CSN4_HUMAN; DCH4; JAB1 containing signalosome subunit 4; JAB1-containing signalosome subunit 4; MGC94896; 信号转导蛋白亚基4抗体SGN4; Signalosome subunit 4.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Cow, Horse, .

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Immunogen: KLH conjugated synthetic peptide derived from human COPS4.

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信号转导蛋白亚基4抗体Predicted Molecular Weight: 46kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:50-200   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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kl145Ra01Ⅸ型胶原α1(COL9α1)多克隆抗体Polyclonal Antibody to Collagen Type IX Alpha 1 (COL9a1)

kl146Hu01Ⅷ型胶原α1(COL8α1)多克隆抗体Polyclonal Antibody to Collagen Type VIII Alpha 1 (COL8a1)

kl147Hu01Ⅶ型胶原(COL7)多克隆抗体Polyclonal Antibody to Collagen Type VII (COL7)

kl147Mu01Ⅶ型胶原(COL7)多克隆抗体Polyclonal Antibody to Collagen Type VII (COL7)

kl148Hu01Ⅵ型胶原α3(COL6α3)多克隆抗体Polyclonal Antibody to Collagen Type VI Alpha 3 (COL6a3)

kl150Hu01Ⅵ型胶原α1(COL6α1)多克隆抗体Polyclonal Antibody to Collagen Type VI Alpha 1 (COL6a1)

kl150Mu01Ⅵ型胶原α1(COL6α1)多克隆抗体Polyclonal Antibody to Collagen Type VI Alpha 1 (COL6a1)

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