12号染色体开放阅读框49抗体

Quantity size:

0.2ml

Concentration:

1mg/ml12号染色体开放阅读框49抗体   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial 12号染色体开放阅读框49抗体developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene 12号染色体开放阅读框49抗体cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf49 gene product has been provisionally designated C12orf49 pending further characterization.

12号染色体开放阅读框49抗体Also known as:

Chromosome 12 open reading frame 49; Hypothetical protein LOC79794; UPF0454 protein C12orf49 homolog; CL049_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Zebrafish, .

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Immunogen: KLH conjugated synthetic peptide derived from human C12ORF49.

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12号染色体开放阅读框49抗体Predicted Molecular Weight: 24kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:50-200   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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