供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL11342R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml Complexin II/复合素2抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Complexin 1 and Complexin 2, also designated Synaphin 1 and Synaphin 2, contain an a-helical middle domain of approximately 58 amino acids. Complexin 1 and Complexin 2 are expressed in presynaptic terminals of inhibitory and excitatory hippocampal neurons, respectively, and in cytoplasmic pools during early stages of Complexin II/复合素2抗体development. Complexins promote SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) precomplex formation by binding to synaxin with its a-helical domain. Complexins are important regulators of transmitter release at a late step in calcium dependent neurotransmitter release or immediately after the calcium-triggering step of fast Complexin II/复合素2抗体synchronous transmitter release and preceding vesicle fusion. Neurons lacking complexins show reduced transmitter release efficiency due to decreased calcium sensitivity of the synaptic secretion process. Complexin 2 may play a role in LTP (long term potentiation) following tetanic stimulation. A progressive loss of Complexin 2 occurs in the brains of mice carrying the Huntington disease mutation, an autosomal dominant neurodegenerative disorder. Changes in the neurotransmitter release might contribute to the motor, emotional and cognitive dysfunctions seen in these mice.
Also known as:
Complexin II/复合素2抗体Complexin 2; Complexin II; Complexin-2; Complexin2; ComplexinII; CPLX 2; Cplx2; CPLX2_HUMAN; CPX 2; CPX II; CPXII; Hfb1; Synaphin 1; Synaphin-1; Synaphin1; 921 L.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Chicken, Horse, .
●
Immunogen: KLH conjugated synthetic peptide derived from human Complexin II.
●
Complexin II/复合素2抗体Predicted Molecular Weight: 15kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl671Hu01SHC-转化蛋白1(SHC1)多克隆抗体Polyclonal Antibody to SHC-Transforming Protein 1 (SHC1)
kl673Hu01羟甲基胆素合酶(HMBS)多克隆抗体Polyclonal Antibody to Hydroxymethylbilane Synthase (HMBS)
kl674Hu01再生胰岛衍生蛋白1β(REG1β)多克隆抗体Polyclonal Antibody to Regenerating Islet Derived Protein 1 Beta (REG1b)
kl675Hu01再生胰岛衍生蛋白3α(REG3α)多克隆抗体Polyclonal Antibody to Regenerating Islet Derived Protein 3 Alpha (REG3a)
kl675Ra01再生胰岛衍生蛋白3α(REG3α)多克隆抗体Polyclonal Antibody to Regenerating Islet Derived Protein 3 Alpha (REG3a)
kl676Hu01再生胰岛衍生蛋白3γ(REG3γ)多克隆抗体Polyclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g)
kl676Mu01再生胰岛衍生蛋白3γ(REG3γ)多克隆抗体Polyclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g)
kl698Hu01鞘氨醇激酶1(SPHK1)多克隆抗体Polyclonal Antibody to Sphingosine Kinase 1 (SPHK1)
kl707Mu01微管蛋白β1(TUBβ1)多克隆抗体Polyclonal Antibody to Tubulin Beta 1 (TUBb1)
kl711Hu01微管蛋白β3(TUBβ3)多克隆抗体Polyclonal Antibody to Tubulin Beta 3 (TUBb3)
kl748Hu01亲核素α2(KPNα2)多克隆抗体Polyclonal Antibody to Karyopherin Alpha 2 (KPNa2)
kl762Hu01干扰素γ诱导蛋白30(IFI30)多克隆抗体Polyclonal Antibody to Interferon Gamma Inducible Protein 30 (IFI30)
kl765Hu01白介素23受体(IL23R)多克隆抗体Polyclonal Antibody to Interleukin 23 Receptor (IL23R)
kl765Ra01白介素23受体(IL23R)多克隆抗体Polyclonal Antibody to Interleukin 23 Receptor (IL23R)
kl767Hu01白介素22受体α2(IL22Rα2)多克隆抗体Polyclonal Antibody to Interleukin 22 Receptor Alpha 2 (IL22Ra2)
kl767Mu01白介素22受体α2(IL22Rα2)多克隆抗体Polyclonal Antibody to Interleukin 22 Receptor Alpha 2 (IL22Ra2)
kl767Ra01白介素22受体α2(IL22Rα2)多克隆抗体Polyclonal Antibody to Interleukin 22 Receptor Alpha 2 (IL22Ra2)
kl777Hu01免疫球蛋白A2(IgA2)多克隆抗体Polyclonal Antibody to Immunoglobulin A2 (IgA2)
kl778Hu01免疫球蛋白A1(IgA1)多克隆抗体Polyclonal Antibody to Immunoglobulin A1 (IgA1)
kl779Hu01膜联蛋白A9(ANXA9)多克隆抗体Polyclonal Antibody to Annexin A9 (ANXA9)
相关产品
关注
拨打电话
留言咨询