cereblon蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml cereblon蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

CRBN is a 442 amino acid protein which is highly concentrated in human brain tissue. CRBN functions are thought to be related to energy metabolism, learning and memory. Localized to the cytoplasm, cereblon蛋白抗体CRBN acts as a protease in mitochondria and is thought to regulate the assembly of KCNT1, as well as the surface expression of KCNT1 in brain regions known to affect memory and learning, such ascereblon蛋白抗体 the hippocampus. The gene encoding CRBN belongs to a family of ATP-dependent lon proteases that play a role in membrane trafficking and proteolysis. Defects in the CRBN gene are associated with mild mental retardation.

Also known as:

Cereblon; DKFZp781K0715; MGC27358; MRT2A; OTTHUMP00000209555; piL; Protein cereblon; Protein x 0001;cereblon蛋白抗体 2610203G15Rik; 2900045O07Rik; AF229032; AW108261; CRBN_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, .

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cereblon蛋白抗体Immunogen: KLH conjugated synthetic peptide derived from human CRBN (210-288aa).

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Predicted Molecular Weight: 51kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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