表皮生长因子样蛋白2抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 表皮生长因子样蛋白2抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Drosophila Flamingo is a seven pass transmembrane cadherin that is necessary for dendritic patterning and axon guidance. Flamingo mammalian homo-logs play similar roles in neuronal development,表皮生长因子样蛋白2抗体 during which they play an important role in cell-cell signaling. Cadherin EGF LAG seven pass G-type receptors (CELSRs) are multi-pass membrane proteins that belong to the G protein-coupled receptor family of proteins. Silencing CELSR2 gene ex-pression results in signficant simplification of dendritic arbors of cortical pyramidal neurons and Purkinje neurons, which may be due to branch retraction. In mouse, CELSR1, CELSR2 and CELSR3 are expressed in the nervous system at early developmental stages, and show expression patterns in the developing CNS. 表皮生长因子样蛋白2抗体CELSR2 is distributed at intercellular boundaries in the whisker and on processes of neuronal cells such as hippocampal pyramidal cells, Purkinje cells and olfactory neurons.

Also known as:

表皮生长因子样蛋白2抗体Cadherin EGF LAG seven pass G type receptor 2 flamingo Drosophila homolog; Cadherin EGF LAG seven-pass G-type receptor 2; Cadherin family member 10; CDHF10; CELR2_HUMAN; Celsr2; EGF like domain multiple 2; EGF-like protein 2; EGFL2; epidermal growth factor like 2; Epidermal growth factor-like protein 2; Flamingo homolog 3; Flamingo1; KIAA0279; MEGF3; Multiple EGF-like domains protein 3; Multiple epidermal growth factor-like domains protein 3.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human CELSR2.

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表皮生长因子样蛋白2抗体Predicted Molecular Weight: 314kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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