补体4结合蛋白

Quantity size:

0.2ml

Concentration:

1mg/ml  补体4结合蛋白 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

C4BPB is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein,补体4结合蛋白 a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. 补体4结合蛋白The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants

补体4结合蛋白Also known as:

C4b binding protein beta chain; C4b-binding protein beta chain; C4BP; C4BPB; C4BPB_HUMAN; Complement component 4 binding protein beta; Complement component 4 binding protein beta chain; Complement component 4-binding protein beta; OTTHUMP00000034288; OTTHUMP00000034289; OTTHUMP00000034375; OTTHUMP0000003474; Proline rich protein; PRP.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Rat, Dog, .

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Immunogen: KLH conjugated synthetic peptide derived from human C4 binding protein .

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补体4结合蛋白Predicted Molecular Weight: 26kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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