阳离子通道精子相关蛋白β亚基抗体

Quantity size:

0.2ml

Concentration:

1mg/ml  阳离子通道精子相关蛋白β亚基抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

CatSpers are ion transport proteins located on the surface of sperm cells in the principal piece of the sperm tail. CatSpers are vital to sperm motility, fertilization and cAMP-mediated calcium influx in sperm. There are four CatSper proteins in mammalian sperm, 阳离子通道精子相关蛋白β亚基抗体namely CatSper (or CatSper1), CatSper2, CatSper3 and CatSper4. CatSper proteins are believed to assemble into a heterotetrameric complex, forming an alkalinization-activated Ca2+-selective channel. CatSper∫ is a multipass membrane protein that functions as an auxiliary protein of the CatSper channel. It contains a large extracellular domain and a number of N-glycosylation sites.  阳离子通道精子相关蛋白β亚基抗体CatSper∫ specifically interacts with CatSper1 and through this interaction plays an important role in the hyperactivated motility of sperm cells, a process that is required in the preparation of sperm for fertilization.

Also known as:

 阳离子通道精子相关蛋白β亚基抗体C14orf161; Cation channel sperm-associated protein subunit beta; Cation channel, sperm-associated, beta; Catsper channel auxiliary subunit beta; CatSper(beta); CATSPERB; FLJ14298; CTSRB_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, .

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Immunogen: KLH conjugated synthetic peptide derived from human CATSPERB.

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 阳离子通道精子相关蛋白β亚基抗体Predicted Molecular Weight: 127kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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