细胞因子诱导蛋白29kDa抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 细胞因子诱导蛋白29kDa抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

CIP29 is a 210 amino acid nuclear protein whose expression is upregulated by erythropoietin. Induction of CIP2 expression is associated with cell cycle progression and apoptosis. This transcription factor细胞因子诱导蛋白29kDa抗体 binds both single stranded (ss) and double stranded (ds) DNA, though it has higher affinity for ssDNA. CIP29 is expressed at low levels in pancreas, spleen, testis, liver, kidney, heart and thymus, and is found to be expressed at higher levels in pancreatic adenocarcinoma and hepatocellular carcinoma. A translocation t(11;12)(q23;q13) in acute myelomonocytic leukemia results in the细胞因子诱导蛋白29kDa抗体 coding region of CIP29 gene fused to exon 9 of the MLL gene, which encodes for a protein with the N-terminal SAP domain and two C-terminal nuclear localization signals of CIP29 and N-termial AT hooks and central DNA methyltransferase homology region of MLL.

Also known as:

Cytokine induced protein of 29 kDa; Cytokine-induced protein of 29 kDa; HCC 1; HCC1; HSPC316; Nuclear protein Hcc 1; Nuclear protein Hcc-1; Proliferation associated cytokine inducible protein CIP29;细胞因子诱导蛋白29kDa抗体 Proliferation-associated cytokine-inducible protein CIP29; SAP domain-containing ribonucleoprotein; SARNP; SARNP_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, .

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Immunogen: KLH conjugated synthetic peptide derived from human CIP29.

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Predicted Molecular Weight: 24kDa.

细胞因子诱导蛋白29kDa抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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