供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL13974R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml Caspase抑制剂COP蛋白抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation.Caspase抑制剂COP蛋白抗体 Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, Caspase抑制剂COP蛋白抗体possibly by preventing the interaction between CASP1 and RIPK2.
Also known as:
CAR16_HUMAN; CARD only domain-containing protein 1; CARD only protein; CARD16; Caspase recruitment domain family, member 16; Caspase recruitment domain-containing protein 16; Caspase-1 dominant-negative inhibitor pseudo-ICE; Caspase-1 inhibitor COP; COP; COP1; Pseudo interleukin-1 beta converting enzyme; Pseudo interleukin-1beta converting enzyme; Caspase抑制剂COP蛋白抗体PSEUDO-ICE.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Chimpanzee, Gorilla.
●
Immunogen: KLH conjugated synthetic peptide derived from human COP1.
●
Predicted Molecular Weight: 23kDa.
Storage:
Caspase抑制剂COP蛋白抗体Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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