环腺苷酸应答元件结合蛋白样蛋白2抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 环腺苷酸应答元件结合蛋白样蛋白2抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, 环腺苷酸应答元件结合蛋白样蛋白2抗体frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization.环腺苷酸应答元件结合蛋白样蛋白2抗体 This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene. [provided by RefSeq, Jul 2008]

Also known as:

环腺苷酸应答元件结合蛋白样蛋白2抗体cAMP responsive element binding protein like 2; CREBL 2; MGC117311; MGC138362; MHBs-binding protein 1; CRBL2_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human CREBL2.

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Predicted Molecular Weight: 14kDa.

环腺苷酸应答元件结合蛋白样蛋白2抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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