补体调节蛋白Crry抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 补体调节蛋白Crry抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Human membrane cofactor protein (MCP), also designated CD46, is a widely distributed complement regulator. In mouse, expression of MCP is largely restricted to testis, while a related widely expressed protein (Crry) appears to perform the regulatory activity of MCP.补体调节蛋白Crry抗体 Crry (for murine complement receptor-related gene Y), protects the body from damage inflicted by inflammation and modulates renal interstitial disease induced by proteinuria. A functional ortholog of human decay-accelerating factor (DAF, CD55) and membrane cofactor protein (MCP, CD46), Crry protects cells from homologous complement by inhibiting the complement proteins C3 and C4 convertases from marking foreign cells for destruction. Sequence analysis suggests that Crry may be the mouse genetic homolog of the CD35 antigen encoded by the human gene CR1.补体调节蛋白Crry抗体 Manipulation of Crry may play a role in treating central nervous conditions such as traumatic brain injury or stroke. Deletion of the gene encoding Crry may play a role in miscarriages.

Also known as:

Antigen 5I2; Complement C4b binding protein CR 1 like protein; Complement component (3b/4b) receptor 1 like; Complement component receptor 1 like protein; Complement regulatory protein Crry; CR1L; Crry; CRRY_RAT; MGC129536.

补体调节蛋白Crry抗体Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Mouse, Rat, .

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Immunogen: KLH conjugated synthetic peptide derived from human Crry.

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Predicted Molecular Weight: 58kDa.

补体调节蛋白Crry抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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