供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL14182R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 细胞色素P450 3A5抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. 细胞色素P450 3A5抗体This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2010]
Also known as:
细胞色素P450 3A5抗体Aryl hydrocarbon hydroxylase; CP 35; CP35; CP3A5_HUMAN; CYP3A5; CYPIIIA5; Cytochrome P 450; Cytochrome P450 3A5; Cytochrome P450; Cytochrome P450 family 3 subfamily A polypeptide 5; Cytochrome P450 HLp2; Cytochrome P450 subfamily IIIA (niphedipine oxidase) polypeptide 5; Cytochrome P450 subfamily IIIA polypeptide 5; Cytochrome P450-PCN3; DKFZp686L16231; Flavoprotein linked monooxygenase; FLJ31317; HLp 2; 细胞色素P450 3A5抗体HLp2; Microsomal monooxygenase; Niphedipine oxidase; P450 PCN3; P450PCN3; PCN 3; PCN3; Xenobiotic monooxygenase.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, .
●
Immunogen: KLH conjugated synthetic peptide derived from human Cytochrome P450 3A5.
●
细胞色素P450 3A5抗体Predicted Molecular Weight: 57kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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