| 供货周期： | 现货 |
| 品牌： | 康朗生物 |
| 规格： | 0.1ml/0.2ml |
| 货号： | KL20043R |
| CAS号： |
Quantity size:
0.2ml
Concentration:
1mg/ml 趋化样因子受体1抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Chemokine-Like Receptor 1 (CMKLR1) is a serpentine transmembrane G-protein linked receptor. It is an orphan chemoattractant receptor, also known as ChemR23 or DEZ. CMKLR1 is expressed on the surface of monocyte-derived immature dendritic cells and peripheral plamacytoid dendritic (pDC) cells; 趋化样因子受体1抗体 but not on myeloid dendritic (mDC) cells, monocytes and lymphocytes. The expression of CMKLR1 on pDC is down-regulated after activation. Chemerin (TIG2) is a natural ligand of CMKLR1. The interaction of CMKLR1 with Chemerin induces pDC activation and chemotaxis. It has been shown that CMKLR1 is a coreceptor for several strains of SIV and HIV-1. CMKLR1 is a potential useful marker for distinguishing pDCs and mDCs.
趋化样因子受体1抗体 Also known as:
Chemokine receptor-like 1; CHEMR23; ChemR23; DEZ; Chemokine like receptor 1; G protein coupled receptor ChemR23; G protein coupled receptor DEZ; CML1_HUMAN ; Orphan G protein coupled receptor.
Specificity:
●
Rabbit Polyclonal IgG, 趋化样因子受体1抗体 affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Rabbit, Guinea Pig, .
●
Immunogen: KLH conjugated synthetic peptide derived from human CMKLR1.
●
趋化样因子受体1抗体 Predicted Molecular Weight: 41kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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