脱氧胞苷激酶抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 脱氧胞苷激酶抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Deoxycytidine kinase is responsible for the phosphorylation of several deoxyribonucleosides and their analogs. Deficiency of this enzyme activity is associated with resistance to脱氧胞苷激酶抗体 antiviral and anticancer chemotherapeutic agents, whereas increased enzyme activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. It is the rate limiting enzyme in the activation of many important anticancer and retroviral drugs and its activity is often decreased in cells that are resistant to cytosine arabinoside.

脱氧胞苷激酶抗体Also known as:

DCK; dCK; DCK protein; DCK_HUMAN; Deoxycytidine kinase; EC 2.7.1; EC 2.7.1.74; MGC117410; MGC138632; OTTHUMP00000219118; OTTHUMP00000219119.

Specificity:

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Rabbit Polyclonal IgG, 脱氧胞苷激酶抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Pig, Horse, .

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Immunogen: KLH conjugated synthetic peptide derived from human DCK.

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Predicted Molecular Weight: 31kDa.

Storage:

脱氧胞苷激酶抗体Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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