血管紧张素Ⅱ抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 血管紧张素Ⅱ抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I,血管紧张素Ⅱ抗体 is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

血管紧张素Ⅱ抗体Also known as:

Alpha 1 antiproteinase, antitrypsin; Ang II; ANG III; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; Angiotensinogen (serpin peptidase inhibitor, clade A member 8); ANHU; Pre angiotensinogen; Serine (or cysteine) proteinase inhibitor; Serpin A8; SERPINA8; 血管紧张素Ⅱ抗体AT-2; AT-II; ANGT_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Horse, Sheep, .

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Immunogen: KLH conjugated synthetic peptide of human Angiotensin II (DRVYIHPF).

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Predicted Molecular Weight: 53kDa.

血管紧张素Ⅱ抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user

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