活化转录因子1抗体

参考价:面议
供货周期: 现货
品牌: 康朗生物
规格: 0.1ml/0.2ml
货号: KL0517R
CAS号:
上海康朗生物科技有限公司
银牌会员9年生产商
关注展位 全部试剂
产品详情

Quantity size:

0.2ml

Concentration:

1mg/ml 活化转录因子1抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

ATF1 (Activating Transcription Factor 1, TREB-36) is a member of the ATF/CREB family of basic region leucine-zipper (bZip) DNA-binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes. Many of these genes are important in cell growth and differentiation,活化转录因子1抗体 and in stress and immune responses. The activation function of CRE-binding proteins may be modulated by phosphorylation of several kinases and is mediated by coactivators such as CREB-binding protein (CBP) and p300. ATF1 is a nuclear protein that binds DNA as a homodimer or as heterodimers with the inducible transcription factors CREB1 or CREM. Heterodimers appear to be stronger transcriptional activators than the homodimers. Tissue expression of ATF1 mRNA is widespread. Several isoforms of ATF1 arise by differential splicing. 活化转录因子1抗体ATF1 mediates both Ca2+ and cAMP responses at several levels. It binds to the Tax-responsive element (TRE1) of the human T-cell lymphotropic virus type-I (HTLV1). ATF1 is detectable in metastatic melanoma cells and seems to contribute to their survival. A chimeric protein composed of the N-terminal domain of EWS (Ewing sarcoma oncogene) linked to the bZip domain of ATF1 is implicated in the rare malignant clear cell sarcoma of tendon sheath and aponeuroses (malignant melanoma of soft parts).

活化转录因子1抗体Also known as:

Activating Transcription Factor1; TREB36 protein; ATF 1; ATF1 EWS fusion gene ATF1 FUS fusion gene; cAMP dependent transcription factor 1; Cyclic AMP dependent transcription factor ATF 1; Cyclic AMP dependent transcription factor ATF1; EWS AFT1; FUS ATF 1; RNA binding protein activating transcription factor 1 fusion protein; TREB 36; TREB36; ATF1_HUMAN.

Specificity:

Rabbit Polyclonal IgG, affinity purified by Protein A.

Reacts with: Human, Mouse, Rat, .

Immunogen: KLH conjugated synthetic peptide derived from human ATF1.

活化转录因子1抗体Predicted Molecular Weight: 29kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl047Ca01肝细胞生长因子(HGF)多克隆抗体Polyclonal Antibody to Heklocyte Growth Factor (HGF)

kl047Hu01肝细胞生长因子(HGF)多克隆抗体Polyclonal Antibody to Heklocyte Growth Factor (HGF)

kl047Mu01肝细胞生长因子(HGF)多克隆抗体Polyclonal Antibody to Heklocyte Growth Factor (HGF)

kl047Ra01肝细胞生长因子(HGF)多克隆抗体Polyclonal Antibody to Heklocyte Growth Factor (HGF)

kl047Rb51肝细胞生长因子(HGF)多克隆抗体Polyclonal Antibody to Heklocyte Growth Factor (HGF)

kl048Hu01抑制素βE(INHβE)多克隆抗体Polyclonal Antibody to Inhibin Beta E (INHbE)

kl048Ra01抑制素βE(INHβE)多克隆抗体Polyclonal Antibody to Inhibin Beta E (INHbE)

kl051Bo01胰岛素样生长因子2(IGF2)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)

kl051Cp01胰岛素样生长因子2(IGF2)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)

kl051Eq01胰岛素样生长因子2(IGF2)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)

kl051Ga01胰岛素样生长因子2(IGF2)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)

kl051Gu01胰岛素样生长因子2(IGF2)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)

kl051Hu01胰岛素样生长因子2(IGF2)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)

kl051Mu01胰岛素样生长因子2(IGF2)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)

kl051Po01胰岛素样生长因子2(IGF2)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)

kl051Ra01胰岛素样生长因子2(IGF2)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)

kl051Rb51胰岛素样生长因子2(IGF2)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)


活化转录因子1抗体信息由上海康朗生物科技有限公司为您提供,如您想了解更多关于活化转录因子1抗体报价、型号、参数等信息, 欢迎来电或留言咨询。除供应活化转录因子1抗体外,上海康朗生物科技有限公司还可为您提供活化转录因子5抗体、转录因子COUP1抗体等产品, 公司有专业的客户服务团队,是您值得信赖的合作伙伴。

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