供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL0518R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 活化复制因子2抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
ATF2 is a member of the ATF/CREB family of basic region leucine zipper DNA binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes. Many of these genes are important in cell growth and differentiation, and in stress and immune responses.活化复制因子2抗体 ATF2 is a nuclear protein that binds DNA as a dimer and can form dimers with members of the ATF/CREB and Jun/Fos families. It is a stronger activator as a heterodimer with cJun than as a homodimer. Several isoforms of ATF2 arise by differential splicing. The stable native full length ATF2 is transcriptionally inactive as a result of an inhibitory direct intramolecular interaction of its carboxy terminal DNA binding domain with the amino terminal transactivation domain. 活化复制因子2抗体Following dimerization ATF2 becomes a short lived protein that undergoes ubiquitination and proteolysis, seemingly in a protein phosphatase-dependent mechanism. Stimulation of the transcriptional activity of ATF2 occurs following cellular stress induced by several genotoxic agents, inflammatory cytokines, and UV irradiation. This activation requires phosphorylation of two threonine residues in ATF2 by both JNK/SAP kinase and p38 MAP kinase. ATF2 is abundantly expressed in brain.
Also known as:
活化复制因子2抗体CREB 2; HB 16; Activating Transcription Factor 2; ATF 2; Atf-2; ATF2 protein; cAMP Response Element Binding Protein 2; cAMP response element binding protein CRE BP1; cAMP-dependent transcription factor ATF-2; cAMP-responsive element-binding protein 2; CRE BP1; CRE-BP; CREB 2; CREB2; CREBP1; Cyclic AMP dependent transcription factor ATF 2; Cyclic AMP-responsive element-binding protein 2; HB 16; HB16; ATF2_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, .
●
Immunogen: KLH conjugated synthetic peptide derived from human ATF2 C-terminus.
●
活化复制因子2抗体Predicted Molecular Weight: 55kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl052Bo01胰岛素样生长因子结合蛋白1(IGFBP1)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 1 (IGFBP1)
kl052Cp01胰岛素样生长因子结合蛋白1(IGFBP1)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 1 (IGFBP1)
kl052Fi01胰岛素样生长因子结合蛋白1(IGFBP1)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 1 (IGFBP1)
kl052Ga01胰岛素样生长因子结合蛋白1(IGFBP1)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 1 (IGFBP1)
kl052Hu01胰岛素样生长因子结合蛋白1(IGFBP1)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 1 (IGFBP1)
kl052Mu01胰岛素样生长因子结合蛋白1(IGFBP1)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 1 (IGFBP1)
kl052Po01胰岛素样生长因子结合蛋白1(IGFBP1)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 1 (IGFBP1)
kl052Ra01胰岛素样生长因子结合蛋白1(IGFBP1)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 1 (IGFBP1)
kl053Bo01胰岛素样生长因子结合蛋白2(IGFBP2)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2)
kl053Hu01胰岛素样生长因子结合蛋白2(IGFBP2)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2)
kl053Mu01胰岛素样生长因子结合蛋白2(IGFBP2)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2)
kl053Po01胰岛素样生长因子结合蛋白2(IGFBP2)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2)
kl053Ra01胰岛素样生长因子结合蛋白2(IGFBP2)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2)
kl054Bo01胰岛素样生长因子结合蛋白3(IGFBP3)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 3 (IGFBP3)
kl054Cp01胰岛素样生长因子结合蛋白3(IGFBP3)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 3 (IGFBP3)
kl054Eq01胰岛素样生长因子结合蛋白3(IGFBP3)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 3 (IGFBP3)
kl054Fi01胰岛素样生长因子结合蛋白3(IGFBP3)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 3 (IGFBP3)
kl054Ga01胰岛素样生长因子结合蛋白3(IGFBP3)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 3 (IGFBP3)
kl054Hu01胰岛素样生长因子结合蛋白3(IGFBP3)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 3 (IGFBP3)
kl054Mu01胰岛素样生长因子结合蛋白3(IGFBP3)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 3 (IGFBP3)
相关产品
关注
拨打电话
留言咨询