含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族2抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族2抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The ankyrin repeat and SOCS box containing (ASB) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is 含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族2抗体thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The gene is induced by all trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation.含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族2抗体 Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.

Also known as:

Ankyrin repeat and SOCS box 2 containing protein; Ankyrin repeat and SOCS box containing 2; Ankyrin repeat and SOCS box containing protein 2; Ankyrin repeat containing protein ASB2.ASB2_HUMAN

Specificity:

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Rabbit Polyclonal IgG,含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族2抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Pig, Cow, Horse, .

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Immunogen: KLH conjugated synthetic peptide derived from human Drebrin..

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Predicted Molecular Weight: 65kDa.

Storage:

含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族2抗体Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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