肿瘤细胞调亡素/肿瘤坏死因子受体死亡受体6抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 肿瘤细胞调亡素/肿瘤坏死因子受体死亡受体6抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

May activate NF-kappa-B and promote apoptosis. May activate JNK and be involved in T-cell differentiation. Required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP).肿瘤细胞调亡素/肿瘤坏死因子受体死亡受体6抗体 N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).
Tissue specificity: Highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. Detected at lower levels in lung, skeletal muscle, kidney, testis, uterus, small intestine, colon, spleen, bone marrow and fetal liver. Very low levels were found in adult liver and peripheral blood leukocytes.

肿瘤细胞调亡素/肿瘤坏死因子受体死亡受体6抗体Also known as:

TNFRSF 21; BM 018; BM018; CD358; Death receptor 6; DR 6; MGC31965; TNFR related death receptor 6; TNFRSF21; TNFRSF21 protein; TNR21_HUMAN; Tumor necrosis factor receptor superfamily member 21; Tumor necrosis factor receptor superfamily member 21 precursor.

Specificity:

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Rabbit Polyclonal IgG, 肿瘤细胞调亡素/肿瘤坏死因子受体死亡受体6抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human DR6/CD358.

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Predicted Molecular Weight: 52/68kDa.

肿瘤细胞调亡素/肿瘤坏死因子受体死亡受体6抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:50-300  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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