有丝分裂控制蛋白样DIS3L2抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 有丝分裂控制蛋白样DIS3L2抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3’ to 5’ exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3’有丝分裂控制蛋白样DIS3L2抗 region. DIS3L2 (DIS3-like exonuclease 2) is an 885 amino acid protein that is thought to function as an exonuclease and may be required for the 3’ processing of pre-mRNA into mature mRNA. Defects or chromosomal translocations involving the gene encoding DIS3L2 may be associated with Marfanoid habitus, a genetic disorder characterized by abnormalities in the skeleton,有丝分裂控制蛋白样DIS3L2抗 eyes and cardiovascular system. DIS3L2 is expressed as five isoforms due to alternative splicing events.

有丝分裂控制蛋白样DIS3L2抗Also known as:

DIS3 L2; DIS3 mitotic control homolog (S. cerevisiae) like 2; DIS3 mitotic control homolog like 2; FLJ36974; MGC42174; DI3L2_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human DIS3L2.

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有丝分裂控制蛋白样DIS3L2抗Predicted Molecular Weight: 99kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:50-200   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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