表皮乳头源性蛋白6抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 表皮乳头源性蛋白6抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

DERP6, is a 316 amino acid protein that localizes to the cytoplasm and exists as multiple alternatively spliced isoforms. Expressed ubiquitously with highest expression in liver, heart, testis, brain and skeletal muscle, DERP6 is thought to be involved in p53-mediated transcriptional regulation. The gene encoding DERP6 maps to human chromosome 17, 表皮乳头源性蛋白6抗体which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, 表皮乳头源性蛋白6抗体BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

表皮乳头源性蛋白6抗体Also known as:

MST071; MSTP071; chromosome 17 open reading frame 81; Dermal papilla derived protein 6; dermal papilla-derived protein 6; DERP6; HSPC002; S phase 2 protein; ELP5_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Pig, Cow, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human DERP6/C1.

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Predicted Molecular Weight: 35kDa.

表皮乳头源性蛋白6抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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