Dapper2蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml  Dapper2蛋白抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Dapper2 is a 774 amino acid protein that exists as multiple alternatively spliced isoforms and is a mammalian homolog of the Xenopus laevis protein dapper. Containing a C-terminal PDZ-binding motif, Dapper2 is thought to promote the lysosomal degradation of nodal receptors,Dapper2蛋白抗体 possibly functioning to negatively regulate the nodal signaling pathway. The gene encoding Dapper2 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Dapper2蛋白抗体Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

Dapper2蛋白抗体Also known as:

bA503C24.7; C6orf116; Chromosome 6 open reading frame 116; Dact2; DACT2_HUMAN; Dapper antagonist of beta catenin homolog 2; Dapper antagonist of beta catenin homolog 2 Xenopus laevis; Dapper homolog 2 antagonist of beta catenin; Dapper homolog 2 antagonist of beta catenin xenopus; Dapper homolog 2; DAPPER2; DPR2; FLJ31232; MGC133141; MGC133142 ; RP11 503C24.7.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, .

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Immunogen: KLH conjugated synthetic peptide derived from human Dact2.

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Dapper2蛋白抗体Predicted Molecular Weight: 83kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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