锌离子结合蛋白DTX2抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 锌离子结合蛋白DTX2抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

DTX2 belongs to the Deltex family. It contains one RING-type zinc finger and two WWE domains. DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. 锌离子结合蛋白DTX2抗体It probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context; mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. DTX2 also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate 锌离子结合蛋白DTX2抗体the Notch pathway via some ubiquitin ligase activity. The WWE domains are thought to mediate some protein-protein interaction, and are frequently found in ubiquitin ligases. There are two named isoforms.

Also known as:

锌离子结合蛋白DTX2抗体Deltex 2; Deltex2; hDTX2; Highly similar to hPMSR6 [H.sapiens]; Protein deltex 2; RING finger protein 58; RNF58; Zinc ion binding protein; DTX2_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Horse, Zebrafish, .

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Immunogen: KLH conjugated synthetic peptide derived from human DTX2.

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Predicted Molecular Weight: 67kDa.

锌离子结合蛋白DTX2抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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