脑神经细胞胞浆蛋白1抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 脑神经细胞胞浆蛋白1抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

NSG1 is a single pass type II membrane protein belonging to the NSG family. It is highly expressed during neuronal maturation but its expression is downregulated in adult tissues. NEEP21 predominantly localizes to Rab 4-positive early endosomes in the somatodendritic neuronal compartment and is essential for proper receptor sorting and recycling in neurons.脑神经细胞胞浆蛋白1抗体 It associates with GRIP1 and GluR-2 and mediates the surface expression of GluR-2. When this interaction is interrupted, GluR-2 accumulates in early endosomes and leads to changes in evoked synaptic current properties. In addition, NEEP21 forms a complex with the SNARE protein, Syntaxin 13 (also known as Syntaxin 12), and participates in the recycling of transferrin receptors (TFRs) and NTR2 (neurotensin receptor 2).

脑神经细胞胞浆蛋白1抗体Also known as:

D4S234E; Brain neuron cytoplasmic protein 1; Brain specific mRNA b; Bsmrb; Neuron-specific gene family member 1; Neuron-specific protein family member 1; NSG1; NSG1_HUMAN; PEP1； P21; D4S234; NEEP21.

Specificity:

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Rabbit Polyclonal IgG,脑神经细胞胞浆蛋白1抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human NSG1.

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Predicted Molecular Weight: 21kDa.

Storage:

脑神经细胞胞浆蛋白1抗体Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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