供货周期: | 现货 |
品牌: | 康朗生物 |
型号: | 0.1ml/0.2ml |
货号: | KL14323R |
Quantity size:
0.2ml
Concentration:
1mg/ml DHX58蛋白抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
DHX58, is a 678 amino acid protein belonging to the helicase family. LGP2 acts as a negative regulator of host innate immune defense against viruses by binding dsRNA produced during viral replication. DHX58蛋白抗体 The repressor domain of LGP2 binds to RIG-I, a signaling protein involved in host defenses against hepatitis C virus (HCV). By preventing RIG-I multimerization, LGP2 negatively regulates RIG-I-mediated signaling. Localized to the cytoplasm, LGP2 contains one helicase ATP-binding domain and one helicase C-terminal domain.
DHX58蛋白抗体Also known as:
D11LGP2; D11lgp2e; DEXH (Asp Glu X His) box polypeptide 58; DEXH box polypeptide 58; DHX 58; DHX58; DHX58_HUMAN; LGP 2; LGP2; Ortholog of mouse D11lgp2; Probable ATP dependent helicase LGP2; Probable ATP dependent RNA helicase DHX58; Probable ATP-dependent helicase LGP2; Probable DHX58蛋白抗体ATP-dependent RNA helicase DHX58; Protein D11Lgp2 homolog; RIG-I-like receptor LGP2; RLR; RNA helicase LGP2.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, .
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Immunogen: KLH conjugated synthetic peptide derived from human DHX58.
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DHX58蛋白抗体Predicted Molecular Weight: 77kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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