DNA聚合酶δ催化亚单位/DNA pol δ cat抗体

Quantity size:

0.2ml

Concentration:

1mg/ml DNA聚合酶δ催化亚单位/DNA pol δ cat抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

DNA replication, recombination and repair, all of which are necessary for genome stability, require the presence of exonucleases (1). In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches (2).DNA聚合酶δ催化亚单位/DNA pol δ cat抗体 Exonucleases involved in these processes include DNA polymerases, including DNA pol ? and é. DNA pol ? consists of two subunits, p125 which interacts directly with the sliding DNA clamp protein PCNA, and p50 (3,4). DNA pol ? can be regulated by cell cycle proteins (5). DNA pol é is a multiple subunit enzyme, DNA聚合酶δ催化亚单位/DNA pol δ cat抗体the catalytic subunit of which is encoded by the POL2 gene (6,7). The exact reactions catalyzed by DNA pol ? and é on leading and lagging strands have not yet been elucidated.

Also known as:

DNA聚合酶δ催化亚单位/DNA pol δ cat抗体CDC2; CDC2 homolog; DNA directed DNA polymerase delta 1; DNA directed polymerase delta 1; DNA pol delta 1; DNA polymerase delta catalytic subunit; DNA polymerase subunit delta p125; DPOD1_HUMAN; POLD; POLD 1; POLD1; Polymerase (DNA directed) delta 1 catalytic subunit 125kDa; Polymerase DNA directed delta 1 catalytic subunit 125kD.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human DNA Poly.

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Predicted Molecular Weight: 124kDa.

DNA聚合酶δ催化亚单位/DNA pol δ cat抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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