转录因子E2F-1抗体

Quantity size:

0.2ml

Concentration:

1mg/ml转录因子E2F-1抗体   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family.转录因子E2F-1抗体 These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded转录因子E2F-1抗体 within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq, Jul 2008]

Also known as:

转录因子E2F-1抗体E2F 1; E2F transcription factor 1; E2F-1; E2f1 E2F transcription factor 1; KIAA4009; mKIAA4009; OTTHUMP00000030661; PBR 3; PBR3; PRB binding protein E2F 1; PRB-binding protein E2F-1; RBAP 1; RBAP-1; RBAP1; RBBP 3; RBBP-3; RBBP3; RBP 3; RBP3; Retinoblastoma associated protein 1; Retinoblastoma binding protein 3; Retinoblastoma-associated protein 1; Retinoblastoma-binding protein 3; Transcription factor E2F1; E2F1_HUMAN.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, .

●

Immunogen: KLH conjugated synthetic peptide derived from human E2F1.

●

Predicted Molecular Weight: 46kDa.

转录因子E2F-1抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:50-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl943Hu01肽酶抑制因子16(PI16)多克隆抗体Polyclonal Antibody to Peptidase Inhibitor 16 (PI16)

kl971Hu01RNA结合基元蛋白24(RBM24)多克隆抗体Polyclonal Antibody to RNA Binding Motif Protein 24 (RBM24)

kl030Hu01序列相似家族5成员C(FAM5C)多克隆抗体Polyclonal Antibody to Family With Sequence Similarity 5, Member C (FAM5C)

kl142Mu01环氧化合物水解酶4(EPHX4)多克隆抗体Polyclonal Antibody to Epoxide Hydrolase 4 (EPHX4)

kl152Hu01含卷曲螺旋域蛋白3(CCDC3)多克隆抗体Polyclonal Antibody to Coiled Coil Domain Containing Protein 3 (CCDC3)

kl176Mu01血管生成素样蛋白7(ANGPTL7)多克隆抗体Polyclonal Antibody to Angiopoietin Like Protein 7 (ANGPTL7)

kl493Hu01辅酶Q10同源物B(COQ10B)多克隆抗体Polyclonal Antibody to Coenzyme Q10 Homolog B (COQ10B)

kl574Hu01含MOCO硫化酶羧基端域蛋白1(MOSC1)多克隆抗体Polyclonal Antibody to MOCO Sulphurase C-Terminal Domain Containing Protein 1 (MOSC1)

kl724Hu01纺锤体蛋白3(SPIN3)多克隆抗体Polyclonal Antibody to Spindlin 3 (SPIN3)

kl751Hu01谷氨酸脱羧酶样蛋白1(GADL1)多克隆抗体Polyclonal Antibody to Glutamate Decarboxylase Like Protein 1 (GADL1)

kl758Mu01序列相似家族135成员B(FAM135B)多克隆抗体Polyclonal Antibody to Family With Sequence Similarity 135, Member B (FAM135B)

kl877Hu01C1q肿瘤坏死因子相关蛋白9(C1QTNF9)多克隆抗体Polyclonal Antibody to C1q And Tumor Necrosis Factor Related Protein 9 (C1QTNF9)

kl945Hu01RAD54样蛋白2(RAD54L2)多克隆抗体Polyclonal Antibody to RAD54 Like Protein 2 (RAD54L2)

kl965Hu01跨膜蛋白2样蛋白(TMEM2L)多克隆抗体Polyclonal Antibody to Transmembrane Protein 2 Like Protein (TMEM2L)

kl031Mu01Misato同源物1(MSTO1)多克隆抗体Polyclonal Antibody to Misato Homolog 1 (MSTO1)

kl085Hu01血管紧张素1-7(Ang1-7)多克隆抗体Polyclonal Antibody to Angiotensin 1-7 (Ang1-7)

kl092Hu01透明质酸氨基葡糖苷酶1(HYAL1)多克隆抗体Polyclonal Antibody to Hyaluronoglucosaminidase 1 (HYAL1)

kl134Hu01超氧化物歧化酶(SOD)多克隆抗体Polyclonal Antibody to Superoxide Dismutases (SOD)

kl152Hu01丝氨酸蛋白酶33(PRSS33)多克隆抗体Polyclonal Antibody to Protease, Serine 33 (PRSS33)

kl158Hu01酶原粒蛋白16同源物B(ZG16B)多克隆抗体Polyclonal Antibody to Zymogen Granule Protein 16 Homolog B (ZG16B)

kl270Hu01YY肽3(PYY3)多克隆抗体Polyclonal Antibody to Peptide YY 3 (PYY3)