供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL11278R |
CAS号: |
Quantity size:
0.1ml
Concentration:
1mg/ml 磷酸化转录因子E2F1抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
E2F's are DNA binding proteins, which associate with negative regulators, such as the retinoblastoma p107 protein, resulting in an altered rate of gene transcription. The E2F proteins contain several evolutionally conserved domains found in most members of the family磷酸化转录因子E2F1抗体. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, 磷酸化转录因子E2F1抗体E2F2 and E2F3, have an additional cyclin binding domain. E2F1 is proposed to be involved in several cellular processes that range from tumor suppressor, cell progression and oncogenesis. E2F1 overexpression can also drive cells into apoptosis.
Also known as:
E2F1 (phospho T433); E2F1 (phospho Thr433); p-E2F1 (T433); p-E2F1 (Thr433); E2F 1; E2F transcription factor 1; E2F-1; E2f1 E2F transcription factor 1; KIAA4009; mKIAA4009; OTTHUMP00000030661; PBR 3; PBR3; PRB binding protein E2F 1; PRB-binding protein E2F-1; RBAP 1;磷酸化转录因子E2F1抗体 RBAP-1; RBAP1; RBBP 3; RBBP-3; RBBP3; RBP 3; RBP3; Retinoblastoma associated protein 1; Retinoblastoma binding protein 3; Retinoblastoma-associated protein 1; Retinoblastoma-binding protein 3; Transcription factor E2F1; E2F1_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, .
●
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human.
●
磷酸化转录因子E2F1抗体Predicted Molecular Weight: 47kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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kl099Ga01基质金属蛋白酶13(MMP13)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 13 (MMP13)
kl099Hu01基质金属蛋白酶13(MMP13)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 13 (MMP13)
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kl100Mu01基质金属蛋白酶2(MMP2)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 2 (MMP2)
kl100Ra01基质金属蛋白酶2(MMP2)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 2 (MMP2)
kl100Rb51基质金属蛋白酶2(MMP2)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 2 (MMP2)
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kl101Ca01基质金属蛋白酶3(MMP3)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3)
kl101Eq01基质金属蛋白酶3(MMP3)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3)
kl101Hu01基质金属蛋白酶3(MMP3)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3)
kl101Mu01基质金属蛋白酶3(MMP3)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3)
kl101Po01基质金属蛋白酶3(MMP3)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3)
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