ELAVL4蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/mlELAVL4蛋白抗体   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The Elav-like genes encode for a family of RNA-binding proteins. Elav, a Drosophila protein and the first described member, is expressed immediately after neuroblastic differentiation into neurons and is necessary for neuronal differentiation and maintenance. Several mammalian Elav-like proteins, designated HuC, HuD and Hel-N1, are also expressed in postmitotic neurons. An additional mammalian homolog, HuR, which is also designated HuA, ELAVL4蛋白抗体is ubiquitously expressed and is also overexpressed in a wide variety of tumors. Characteristically, these homologs all contain three RNA recognition motifs (RRM) and they specifically bind to AU-rich elements (ARE) in the 3'-untranslated region of mRNAs transcripts. ARE sites target mRNA for rapid degradation and thereby regulate the expression levels of genes involved in cellELAVL4蛋白抗体 growth and differentiation. When Elav-like proteins associate with these ARE sites this degradation is inhibited, leading to an increased stability of the corresponding transcript. Elav proteins function within the nucleus, and they are shuttled between the nucleus and cytoplasm by a nuclear export signal, which is a regulatory feature of the Elav-like proteins as it limits their accessibility to ARE sites.

ELAVL4蛋白抗体Also known as:

ELAV (embryonic lethal abnormal vision Drosophila) like 4; ELAV L4; ELAV like 4; ELAV like protein 4; ELAV-like protein 4; ELAV4_HUMAN; HuD; Elavl4; Embryonic lethal abnormal vision Drosophila homolog of like 4; Hu antigen D; Hu-antigen D; HuD; Paraneoplastic encephalomyelitis antigen HuD; PNEM.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, .

●

Immunogen: KLH conjugated synthetic peptide derived from human ELAVL4.

●

ELAVL4蛋白抗体Predicted Molecular Weight: 42kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl130Mu01组织金属蛋白酶抑制因子4(TIMP4)多克隆抗体Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 4 (TIMP4)

kl130Po01组织金属蛋白酶抑制因子4(TIMP4)多克隆抗体Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 4 (TIMP4)

kl130Ra01组织金属蛋白酶抑制因子4(TIMP4)多克隆抗体Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 4 (TIMP4)

kl130Rb51组织金属蛋白酶抑制因子4(TIMP4)多克隆抗体Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 4 (TIMP4)

kl131Bo01转化生长因子β诱导蛋白(TGFβI)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta Induced Protein (TGFbI)

kl131Fi01转化生长因子β诱导蛋白(TGFβI)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta Induced Protein (TGFbI)

kl131Hu01转化生长因子β诱导蛋白(TGFβI)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta Induced Protein (TGFbI)

kl131Mu01转化生长因子β诱导蛋白(TGFβI)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta Induced Protein (TGFbI)

kl131Po01转化生长因子β诱导蛋白(TGFβI)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta Induced Protein (TGFbI)

kl131Rb51转化生长因子β诱导蛋白(TGFβI)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta Induced Protein (TGFbI)

kl132Hu01脂联素受体2(ADIPOR2)多克隆抗体Polyclonal Antibody to Adiponectin Receptor 2 (ADIPOR2)

kl132Ra01脂联素受体2(ADIPOR2)多克隆抗体Polyclonal Antibody to Adiponectin Receptor 2 (ADIPOR2)

kl134Bo01肿瘤坏死因子β(TNFβ)多克隆抗体Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb)

kl134Ca01肿瘤坏死因子β(TNFβ)多克隆抗体Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb)

kl134Hu01肿瘤坏死因子β(TNFβ)多克隆抗体Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb)

kl134Mu01肿瘤坏死因子β(TNFβ)多克隆抗体Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb)

kl134Po01肿瘤坏死因子β(TNFβ)多克隆抗体Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb)

kl134Ra01肿瘤坏死因子β(TNFβ)多克隆抗体Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb)

kl134Rb51肿瘤坏死因子β(TNFβ)多克隆抗体Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb)

kl134Si01肿瘤坏死因子β(TNFβ)多克隆抗体Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb)