供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL13120R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 多发性肌炎/硬皮病自身抗原2抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The exosome is a multi-subunit complex composed of several highly conserved proteins, some of which are 3’ to 5’ exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3’ region. EXOSC10, also known as PMSCL, PMSCL2, p2, p3, 多发性肌炎/硬皮病自身抗原2抗体p4, RRP6, Rrp6p, PM-Scl, or PM/Scl-100, is an 885 amino acid protein that contains one HRDC domain and one 3’-5’ enonuclease domain. Localized to both the cytoplasm and the nucleus, EXOSC10 is part of the post-splicing exosome complex and is involved in mRNA surveillance, mRNA nuclear export and nonsense-mediated decay of mRNAs containing premature stop codons. Antibodies against EXOSC10 have been found in patients with scleroderma and/or polymyositis (chronic diseases of the skin and muscle, respectively), 多发性肌炎/硬皮病自身抗原2抗体suggesting that EXOSC10 may be involved in the pathogenesis of these diseases. Two isoforms of EXOSC10 exist due to alternative splicing events.
Also known as:
多发性肌炎/硬皮病自身抗原2抗体Autoantigen PM/Scl 2; Exosc10; Exosome component 10; EXOSX_HUMAN; P100 polymyositis scleroderma overlap syndrome associated autoantigen; P100 polymyositis-scleroderma overlap syndrome-associated autoantigen; p2; p3; p4; PM Scl; PM/Scl 100; PM/Scl-100; PMSCL; PMSCL2; Polymyositis/scleroderma autoantigen 100 kDa; Polymyositis/scleroderma autoantigen 2 100 kDa; Polymyositis/scleroderma autoantigen 2; RRP6; Rrp6p.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, .
●
Immunogen: KLH conjugated synthetic peptide derived from human EXOSC10/.
●
多发性肌炎/硬皮病自身抗原2抗体Predicted Molecular Weight: 101kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl045Mu01存活素(Surv)多克隆抗体Polyclonal Antibody to Survivin (Surv)
kl047Hu01Ki-67蛋白(Ki67P)多克隆抗体Polyclonal Antibody to Ki-67 Protein (Ki67P)
kl047Mu01Ki-67蛋白(Ki67P)多克隆抗体Polyclonal Antibody to Ki-67 Protein (Ki67P)
kl047Ra01Ki-67蛋白(Ki67P)多克隆抗体Polyclonal Antibody to Ki-67 Protein (Ki67P)
kl048Hu01磷脂酶B(PLB)多克隆抗体Polyclonal Antibody to Phospholikle B (PLB)
kl049Hu01磷脂酶D(PLD)多克隆抗体Polyclonal Antibody to Phospholikle D (PLD)
kl050Ca01高迁移率族AT Hook蛋白1(HMGA1)多克隆抗体Polyclonal Antibody to High Mobility Group AT Hook Protein 1 (HMGA1)
kl050Hu01高迁移率族AT Hook蛋白1(HMGA1)多克隆抗体Polyclonal Antibody to High Mobility Group AT Hook Protein 1 (HMGA1)
kl053Hu01高迁移率族AT Hook蛋白2(HMGA2)多克隆抗体Polyclonal Antibody to High Mobility Group AT Hook Protein 2 (HMGA2)
kl054Hu01S100钙结合蛋白P(S100P)多克隆抗体Polyclonal Antibody to S100 Calcium Binding Protein P (S100P)
kl056Hu01基质金属蛋白酶14(MMP14)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 14 (MMP14)
kl056Mu01基质金属蛋白酶14(MMP14)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 14 (MMP14)
kl057Hu01核因子κB受体激活因子(RANκ)多克隆抗体Polyclonal Antibody to Receptor Activator Of Nuclear Factor Kappa B (RANk)
kl057Ra01核因子κB受体激活因子(RANκ)多克隆抗体Polyclonal Antibody to Receptor Activator Of Nuclear Factor Kappa B (RANk)
kl058Hu01白介素20(IL20)多克隆抗体Polyclonal Antibody to Interleukin 20 (IL20)
kl060Hu01血小板衍生生长因子受体α(PDGFRα)多克隆抗体Polyclonal Antibody to Platelet Derived Growth Factor Receptor Alpha (PDGFRa)
kl060Ra01血小板衍生生长因子受体α(PDGFRα)多克隆抗体Polyclonal Antibody to Platelet Derived Growth Factor Receptor Alpha (PDGFRa)
kl061Hu01血小板衍生生长因子受体β(PDGFRβ)多克隆抗体Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb)
kl064Hu01白介素24(IL24)多克隆抗体Polyclonal Antibody to Interleukin 24 (IL24)
kl064Mu01白介素24(IL24)多克隆抗体Polyclonal Antibody to Interleukin 24 (IL24)
kl065Hu01透明质酸介导运动因子受体(HMMR)多克隆抗体Polyclonal Antibody to Hyaluronan Mediated Motility Receptor (HMMR)
kl066Hu01双氧化酶2(DUOX2)多克隆抗体Polyclonal Antibody to Dual Oxidase 2 (DUOX2)
kl066Ra01双氧化酶2(DUOX2)多克隆抗体Polyclonal Antibody to Dual Oxidase 2 (DUOX2)
kl067Hu01去唾液酸糖蛋白受体2(ASGR2)多克隆抗体Polyclonal Antibody to Asialoglycoprotein Receptor 2 (ASGR2)
kl068Hu01VEGF共调节趋化因子1(VCC1)多克隆抗体Polyclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1)
kl070Hu01趋化因子C-基元配体2(XCL2)多克隆抗体Polyclonal Antibody to Chemokine C-Motif Ligand 2 (XCL2)
kl071Bo01干扰素诱导T-细胞α亚族趋化剂(ITαC)多克隆抗体Polyclonal Antibody to Interferon Inducible T-Cell Alpha Chemoattractant (ITaC)
kl071Ra01干扰素诱导T-细胞α亚族趋化剂(ITαC)多克隆抗体Polyclonal Antibody to Interferon Inducible T-Cell Alpha Chemoattractant (ITaC)
相关产品
关注
拨打电话
留言咨询