癌基因ERG3抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 癌基因ERG3抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1–3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1 and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression, and share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear 癌基因ERG3抗体localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. Several of these proteins have been shown to recognize similar motifs in DNA that share a centrally located 5'-GGAA-3' element. Erg genes encode for multiple proteins due to alternative splicing and alternative usage of initiation codons.

癌基因ERG3抗体Also known as:

Avian erythroblastosis virus E-26 (v-ets) oncogene related; D030036I24Rik; Erg 3; Erg; ERG/EWS fusion gene, included; ERG/FUS fusion gene, included; ERG/TMPSSR2 fusion gene, included; ERG_HUMAN; ERG1, included; ERG2, included; ets related; ETS-related gene; KCNH2; Oncogene ERG; p55; TMPRSS2/ERG fusion; transcriptional regulator ERG (transforming protein ERG); 癌基因ERG3抗体Transcriptional regulator ERG; Transforming protein ERG; v ets avian erythroblastosis virus E26 oncogene; v ets avian erythroblastosis virus E26 oncogene related; v ets erythroblastosis virus E26

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Horse, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human ERG3.

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癌基因ERG3抗体Predicted Molecular Weight: 55kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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