ECSIT蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/mlECSIT蛋白抗体   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

ECSIT is a 431 amino acid ubiquitously expressed protein that plays an important role as an adaptor protein in the cytosolic signal transduction cascade events triggered by Toll receptor activation. Within the Toll pathway, ECSIT regulates MEKK1 processing for activation of NFκB, ECSIT蛋白抗体a major event leading to initiation of the innate immune response. In the mitochondria, ECSIT interacts with NDUFAF1 and assists in the formation of NADH:ubiquinone oxidoreductase (complex I), an extremely complicated multiprotein complex located in the inner mitochondrial membrane that functions in the transport of electrons from NADH to ubiquinone. Knockdown of ECSIT results ECSIT蛋白抗体in severely impaired complex I assembly and disturbed mitochondrial function. There are two isoforms of ECSIT that are produced as a result of alternative splicing events

ECSIT蛋白抗体Also known as:

Ecsit; ECSIT homolog; ECSIT protein; ECSIT_HUMAN; Evolutionarily conserved signaling intermediate in Toll pathway; Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Evolutionarily conserved signaling intermediate in Toll pathways; Likely ortholog of mouse signaling intermediate in Toll pathway evolutionarily conserved; Protein SITPEC; Signaling intermediate in Toll pathway evolutionarily conserved; SITPEC; SITPEC protein.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Cow, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human ECSIT.

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Predicted Molecular Weight: 44kDa.

ECSIT蛋白抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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