供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL14489R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml EDEM1蛋白抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Proteins expressed in the endoplasmic reticulum (ER) are subjected to a tight quality control. Terminally misfolded proteins in the endoplasmic reticulum (ER) are retrotranslocated to the cytoplasm and degraded by proteasomes through a mechanism known as ER-associated degradation (ERAD). EDEM (ER degradation-enhancing alpha-mannosidase-like) protein is aEDEM1蛋白抗体 type II membrane protein that localizes to the ER and is directly involved in ERAD. EDEM targets misfolded glycoproteins for degradation in an N-glycan-dependent manner and extracts misfolded glycoproteins from the calnexin cycle. The human EDEM gene maps to chromosome 3p.
EDEM1蛋白抗体Also known as:
EDEM 1; EDEM1_HUMAN; EDEM; Endoplasmic reticulum degradation enhancing alpha mannosidase like protein; ER degradation enhancer, mannosidase alpha like 1; ER degradation enhancing alpha mannosidase like 1; KIAA0212.
Specificity:
●
Rabbit Polyclonal IgG,EDEM1蛋白抗体 affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Horse, .
●
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human.
●
Predicted Molecular Weight: 74kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
EDEM1蛋白抗体Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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