ELMO3蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml ELMO3蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Elmo1 associates with DOCK 180 and may influence phagocytosis and effect cell shape changes. Src family kinase mediated tyrosine phosphorylation of ELMO1 influences signaling through Elmo1/Crk/DOCK 180 pathwaysELMO3蛋白抗体. Elmo2 interacts directly with Rho G in a GTP-dependent manner and forms a ternary complex with DOCK 180 to induce activation of Rac 1. The RhoG-Elmo2-DOCK 180 pathway is required for activation of Rac 1 and cell spreading mediated by integrin, as well as for neurite outgrowth induced by nerve growth factor. Elmo3 acts in assocation with DOCK180 and Crk II and may be required in complex with DOCK180 to activate Rac/Rho small GTPases.

ELMO3蛋白抗体Also known as:

CED 12; Ced 12 homolog 3; CED12; ELMO 3; ELMO3; ELMO3_HUMAN; Engulfment and cell motility 3; Engulfment and cell motility protein 3; FLJ13824.

Specificity:

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Rabbit Polyclonal IgG,ELMO3蛋白抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Guinea Pig, .

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Immunogen: KLH conjugated synthetic peptide derived from human ELMO3.

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Predicted Molecular Weight: 69kDa.

ELMO3蛋白抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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