Ero1-Lβ蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml Ero1-Lβ蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on P4HB/PDI to Ero1-Lβ蛋白抗体transfer oxidizing equivalent. Associates with ERP44 but not with GRP54, demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Acts independentlyEro1-Lβ蛋白抗体 of glutathione. May be responsible for a significant proportion of reactive oxygen species (ROS) in the being a source of oxidative stress. Required for the folding of cell, thereby being a source of oxidative stress.

Ero1-Lβ蛋白抗体Also known as:

Endoplasmic oxidoreductin-1-like protein B; ERO1-L-beta; ERO1B_HUMAN; ERO1-like protein beta; Oxidoreductin-1-L-beta.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Rabbit, Guinea Pig, .

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Immunogen: KLH conjugated synthetic peptide derived from human ERO1LB.

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Predicted Molecular Weight: 50kDa.

Ero1-Lβ蛋白抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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