ETV3蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml ETV3蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

ETV3 belongs to the ETS family of transcription factors and functions as a transcriptional repressor. ETS family members share a highly conserved DNA binding domain and play a role in growth factor pathways regulating proliferation and differentiation. PE-1 is ubiquitously expressed and localizes to the nucleus. Its expression can be induced by IL-10ETV3蛋白抗体 via the STAT3 pathway suggesting that PE-1 contributes to the IL-10 downstream anti-inflammatory effects. During terminal cell differentiation, PE-1 plays a role in growth arrest by specifically repressing the target genes that are involved in Ras-dependent proliferation. The contributions of PE-1 to these anti-proliferative effects are heavily dependent on its interaction with Gemin3. Two PE-1 isoforms exist due to alternative splicing events.

ETV3蛋白抗体Also known as:

AI414410; bA110J1.4; ETS domain transcriptional repressor PE1; ETS family transcriptional repressor; ETS translocation variant 3; ets variant 3; ets variant gene 3; ets variant gene 3, ETS family transcriptional repressor; ETV3; ETV3_HUMAN; ME PE1; METS; Mitogenic Ets transcriptional suppressor; Oncogene PE1; PE 1; PE-1; PE1.

Specificity:

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Rabbit Polyclonal IgG, ETV3蛋白抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human ETV3.

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Predicted Molecular Weight: 57kDa.

ETV3蛋白抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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