FAS凋亡抑制分子3抗体

Quantity size:

0.2ml

Concentration:

1mg/ml FAS凋亡抑制分子3抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing  FAS凋亡抑制分子3抗体expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation. 
 FAS凋亡抑制分子3抗体Tissue specificity: Expressed in lymph nodes, peripheral blood leukocytes, lung, thymus and kidneys. Very weak expression detected in spleen, liver, heart, and salivary gland.

Also known as:

Faim3; FAIM3_HUMAN; Fas apoptotic inhibitory molecule 3; Fc mu receptor; FCMR; IgM Fc receptor; Immunoglobulin mu Fc receptor;  FAS凋亡抑制分子3抗体Regulator of Fas induced apoptosis; Regulator of Fas-induced apoptosis Toso; TOSO.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, .

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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human.

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Predicted Molecular Weight: 41kDa.

 FAS凋亡抑制分子3抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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