甲酰肽受体3抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 甲酰肽受体3抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The N-formyl peptide receptor (FPR) family is comprised of three members, FPR, FPR3 (also designated FPRL1, lipoxin A4 receptor, FPRH1 or FPR2) and FPR like-2 (FPRL2), all of which are chemotactic G protein-coupled receptors that contain seven transmembrane domains. 甲酰肽受体3抗体These receptors are found on the surface of phagocytic leukocytes, such as neutrophils and monocytes, and each family member contains specific residues, which are responsible for determining its ligand specificity. FPR3 is a promiscuous receptor that binds to several ligands, including lipoxin A4, N-formyl-methionyl-leucyl-phenylalanine (fMLP), serum amyloid A (SAA), prion peptide and the 42 amino acid form of beta amyloid. Upon activation, FPR3 induces migration and calcium 甲酰肽受体3抗体mobilization in human monocytes and neutrophils and is involved in inflammatory and host defense responses. FPR3 may mediate inflammation in prion and Alzheimer’s diseases, which makes it a potential target for therapeutic agents.

甲酰肽受体3抗体Also known as:

FML2_HUMAN; FPRH1; FPRH2; FPRL2; Lxa4r; RMLP-R-I; FMLP related receptor II; FMLPY; Formyl peptide receptor 3; Formyl peptide receptor like 2; Lipoxin A4 receptor; LXA4 R; N formyl peptide receptor 3; RGD1566044.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human FPR3/Lip.

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甲酰肽受体3抗体Predicted Molecular Weight: 40kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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